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Wednesday, July 22, 2020 | History

4 edition of Application of apoptosis to cancer treatment found in the catalog.

Application of apoptosis to cancer treatment

Application of apoptosis to cancer treatment

  • 282 Want to read
  • 35 Currently reading

Published by Springer in Dordrecht .
Written in English

    Subjects:
  • Cancer -- Treatment,
  • Apoptosis,
  • Antineoplastic Agents -- therapeutic use,
  • Apoptosis -- drug effects,
  • Neoplasms -- drug therapy

  • Edition Notes

    Statement[edited] by Mels Sluyser.
    ContributionsSluyser, M. 1930-
    Classifications
    LC ClassificationsQH671 .A69 2005
    The Physical Object
    Paginationvi, 370 p. :
    Number of Pages370
    ID Numbers
    Open LibraryOL21575772M
    ISBN 101402033036, 1402033028
    LC Control Number2006275530

    A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that.   In fact, much conventional research has been done to determine whether the treatment actually promotes cancer. In study after study, however, it has been proven that it does not. One way that HBO therapy can affect cancer cells is through a reduction in hypoxia, a low-oxygen condition that is common in cancerous tumors.

      Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. It is also one of the most studied topics among cell biologists. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. In some, the problem is due to too much apoptosis, such as in the case of Cited by: This tissue undergoes apoptosis, which allows the fingers to form. Menstruation, where the lining of the uterus is shed monthly, occurs because of apoptosis. This programmed cellular death also combats cancer by keeping cells from growing uncontrollably. Chemotherapy drugs attack cancerous cells in part by triggering apoptosis.

    An orally active aqueuous extract derived from the plant Scutellaria barbata with potential antineoplastic activity. Sparing normal cells, apoptosis inducer BZL specifically facilitates translocation of the protein apoptosis-inducing factor (AIF) from the mitochondrial membrane into the nucleus in tumor cells, thereby causing tumor cell-specific chromatin condensation and DNA degradation. Apoptosis in Hormone-Dependent Cancers. by. Ernst Schering Foundation Symposium Proceedings (Book 14) Thanks for Sharing! You submitted the following rating and review. We'll publish them on our site once we've reviewed : Springer Berlin Heidelberg.


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Application of apoptosis to cancer treatment Download PDF EPUB FB2

This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER : $ This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients.

Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER : Springer Netherlands. Get this from a library. Application of apoptosis to cancer treatment. Application of apoptosis to cancer treatment book Sluyser;] -- Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body.

This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients.

Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS.

item 3 Application of Apoptosis to Cancer Treatment by Mels. of results for Books: "apoptosis and cancer" Skip to main search results Amazon Prime. Application of Apoptosis to Cancer Treatment. by Mels Sluyser | Jun 1, Goodreads Book reviews & recommendations: IMDb Movies. Application Of Apoptosis To Cancer Treatment This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients.

Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. Application of Apoptosis to Cancer Treatment. By M Sluyser (Ed.).

Springer, Dordrecht, Netherlands: pp. ISBN $, hardcoverCited by: 1. Hence, apoptosis plays an important role in both carcinogenesis and cancer treatment. This article gives a comprehensive review of apoptosis, its mechanisms, how defects along the apoptotic pathway contribute to carcinogenesis and how apoptosis Cited by:   Apoptosis also suppresses tumourigenesis in various other ways.

For example, matrix detachment of cells—a pre-requisite for metastatic disease—induces a form of apoptosis called anoikis. In short, for cancer to initiate and progress, apoptosis must be inhibited at multiple stages.

Cell death also plays key roles in the treatment of by: Despite being the cause of problem, apoptosis plays an important role in the treatment of cancer as it is a popular target of many treatment strategies. The abundance of literature suggests that. The inactivation of programmed cell death, or apoptosis, is central to the development of cancer.

This disabling of apoptotic responses might be a major contributor both to treatment resistance. This unusual and interesting book written by 46 investigators in their respective areas describes the main apoptotic pathways, their dysregulation in most human diseases, and the new therapeutic approaches developed to cure them.

Particular emphasis is given to new strategies of cancer treatment based on apoptosis control. The book successfully combines current knowledge of the basic Author: Alex Philchenkov. Apoptosis is important for removal of damaged cells, and impaired apoptosis is theorized to contribute to the development of cancer (12).

Apoptosis is a physiologic marker of cell death and is. apoptosis listen (A-pop-TOH-sis) A type of cell death in which a series of molecular steps in a cell lead to its death.

This is one method the body uses to get rid of unneeded or abnormal cells. The process of apoptosis may be blocked in cancer cells. Also called programmed cell death. A big challenge for a successful colon cancer treatment is the lack of eradication of the entire tumour cell population and consequent development of chemoresistance.

Control of cell number from tissues and elimination of cells predisposed to malignant transformation, having an aberrant cell cycle or presenting DNA mutations, might be performed by a cellular ‘suicide’ mechanism — the Cited by: 1.

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases.

This book examines various. Apoptosis and Cancer Treatment. Chemotherapy drugs and radiation work by forcing the cancer cells to undergo apoptosis, triggering death signals by causing DNA damage or cellular distress. In addition, many apoptosis-inducing drugs are currently being researched, and some are in clinical trials.

Cell Death - Autophagy, Apoptosis and Necrosis. Edited by: Tobias M. Ntuli. ISBNPDF ISBNPublished Cited by: 3. The role of apoptosis in cancer development and treatment response J.

Martin Brown and Laura D. Attardi OPINION cell death, or apoptosis, is central to the development of cancer. This disabling of apoptotic responses might be a major contributor both to treatment resistanceFile Size: KB.

Activation of apoptosis pathways is a key mechanism by which cytotoxic drugs kill tumor cells. Also immunotherapy of tumors requires an apoptosis sensitive phenotype of target cells.

Defects in apoptosis signalling contribute to resistance of tumors. Activation of apoptosis signalling following treatment with cytotoxic drugs has been shown to lead to activation of the mitochondrial (intrinsic Cited by: Apoptosis is a multi-step, multi-pathway cell-death programme that is inherent in every cell of the body.

In cancer, the apoptosis cell-division ratio is altered. Cancer treatment by chemotherapy and irradiation kills target cells primarily by inducing apoptosis.

Hyperactive apoptosisMeSH: DAbstract. Cancer is one of the most dreaded diseases where the treatment and the possible outcome depend on a multitude of factors.

One of the major obstacles in cancer cure is the drug resistance that the cancer cells develop.